scimaX^®

Continuing Bruker’s tradition to forge productivity from technological innovation, scimaX^®includes several innovative core technologies, to give you performance rivaling high field MRMS at your fingertips.

Patented ParaCell 2xR detector
scimaX^®comes standard with ParaCell 2xR and AMP detection technology. The ParaCell is a departure from traditional MRMS cell strategies and provides uncommon broadband ion stability resulting in resolution orders of magnitude above other detection schemes. The ParaCell in combination with Absorption Mode Processing algorithms is the prerequisite for routine access to Isotopic Fine Structure (IFS) Information.

Bruker’s 2xR MRMS instruments use magnetron control technology and the latest high sensitivity, low noise MRMS preamplifier, realizing scientists' long standing vision to exploit harmonics detection schemes and thus increase the experimental speed and instrument productivity without sacrificing resolving power.

7T conduction cooled magnet technology
Bruker‘s revolutionary 7T superconducting magnet technology is the basis of the smaller footprint scimaX^®MRMS system. This key innovation uses 'conduction cooling' technology, which removes the requirements to fill liquid cryogens or provide quench ducts.

The scimaX^®可以运行在一个标准的实验室空间,在吗abling a wider range of scientific disciplines to gain access to the power of MRMS technology.

Unique ESI/MALDI dual source
Only Bruker instruments allow operation of a unique ESI/MALDI dual source. This source is included with any scimaX^®and can either run liquid samples introduced via the Electrospray ionization (ESI) source or from MALDI samples. This highly sensitive MALDI source uses Bruker's smartbeam-II laser technology and provides several small focus diameters for various applications with different sample preparation techniques. Fast switchover between MALDI and ESI operation is controlled by a software push button, so even simultaneous ESI/MALDI operation is possible.

Ion activation techniques
scimaX^®includes a variety of ion activation techniques, including ECD, ETD, CID, EDD, SORI-CID, MALDI-ISD, and NETD capabilities.

MALDI and MALDI Imaging
scimaX^®is the ultimate MALDI Imaging system for analyzing small to medium sized molecules. Its unrivaled eXtreme Resolution capability and sub-ppm mass accuracy, over a wide mass range, can differentiate images that are only mDa apart and are prerequisite for IFS analysis and formula confirmation.
Analyze complex mixtures directly with the speed and robustness of MALDI. Visualize and map molecular distributions without molecular labels using MALDI Imaging, and determine molecular changes occurring in spatially significant regions of samples.

Phenotypingworkflow for large cohorts
scimaX^®eXtreme Resolution allows for chromatography-free acquisition complementary to established NMR based solutions. The MRMS aXelerate® workflow breaks free of LC throughput limitations and allows analysis of over 200 samples a day. This solution withMetaboScape^®based processing enables automatic annotation of molecular formulae for hundreds of known metabolites and molecular formulae generation for thousands of unknown analytes in complex samples for metabolomics and phenomics studies.

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When seeing every molecule matters, MRMS is mandatory to unravel the potentially hundreds of isobaric species in complex mixture analysis, placing MRMS as the industrial standard for Petroleomics. Now, scimaX^®enables high field performance at 7T, breaking conventional norms for complex mixture analysis.