Languages
Electron paramagnetic resonance detection and pollution of the environment persistent free radicals characteristics research
takeaway
Electron paramagnetic resonance (EPR) spectrometer is a kind of good study environment free radical detection means and instrument information network particularly had an interview with the Chinese Academy of Sciences ecological environmental research center, state key laboratory of environmental chemistry and ecological toxicology liew kueh thon researcher, he tells his story with the EPR, EPFRs.
Liew kueh thon
Electron paramagnetic resonance (EPR) spectrometer is one of the free radical detection instrument analysis technology.EPR in quantum chemistry, physics, medicine, biology, environment and chemistry, etc.) has been employed.Environment and health is a hot topic, among them, the environmental pollution will cause how health effect, also is the important scientific problems of current needs to be answered.Electron paramagnetic resonance in the field of environment and health research may also play an important role.
In addition to the highly reactive Free Radicals and short life of, there is life long Free Radicals in the environment, is known as the environment Persistent Free Radicals (Environmentally Persistent Free Radicals: EPFRs) or long life Free Radicals.EPFRs is put forward the concept of ten years ago, it has a longer half-life and stability, and the remaining time in the environment, increased the exposure duration of the organism, easily induced oxidative stress reaction, can damage cells and the body and so on, is regarded as a new type of environmental pollutants.And actual back in 1900, he's found the first free radicals -- trityl free radicals, and long life free radicals.At present about EPFRs exist in the environment and its environmental effect caused wide attention of researchers at home and abroad, research group progressively more research work.Chinese Academy of Sciences ecological environmental research center, state key laboratory of environmental chemistry and ecological toxicology liew kueh thon researcher in domestic has carried out some early EPFRs related work and achieved good results.
Instrument information network has special interview to liew kueh thon researcher, he tells the story of EPR, EPFRs.
Liew kueh thon main work focused on two aspects: 1. The persistent organic pollutants (remobilised) : such as dioxins, bromine generation of dioxins, polychlorinated naphthalene and halogenated polycyclic aromatic hydrocarbons, such as persistent organic pollutants (POPs), to establish a typical remobilised high sensitivity analysis method, illustrates the remobilised in environment pollution characteristics, find out some potential sources and research on the mechanism and control principle;2. The environment persistent free radicals (EPFRs) : the main research EPFRs environmental pollution characteristics and transformation mechanism of related work.
Asked chose to study the reason which the EPFRs, liew kueh thon introduced to there are two main factors, one is to want to further understand the molecular mechanism of dioxins and other remobilised vital reaction intermediates in the process of detection, using paramagnetic resonance technique can detect reaction in the process of free radical intermediates, to infer molecular mechanism of dioxins.Another reason is that the foundation in 2015 launched a major research project -- atmospheric fine particles of toxicology and health effect.Jiang teacher encouraged me to do "our key laboratory of atmospheric fine particles of free radicals in related research work," said liew kueh thon, "around the year 2015 is haze weather in Beijing is more serious, our team collected the atmospheric samples of fine particulate matter in Beijing, examined the EPFRs, found EPFRs have different distribution in different particle size of particles, the adsorption of fine particles in the EPFRs content is higher, the resulting potential health effects deserves further attention."
The research is published in the international famous magazine in the field of environment ENVIRONMENTAL SCIENCE & TECHNOLOGY (ES&T).
Liew kueh thon in EPFRs related research work mainly using electron paramagnetic resonance spectroscopy and chromatography/mass spectrometry analysis technology, two categories electron paramagnetic resonance spectroscopy technique can detect unpaired electrons, which in the process of reaction free radical intermediates.Chromatography mass spectrometry may carry on the appraisal after the reaction product, used to study the formation mechanism.Liew kueh thon表示，未来希望能将电子顺磁共振和色谱/质谱仪器同时与化学反应器连接使用，同时检测反应中的自由基中间体并鉴定反应后的产物。实验室使用的电子顺磁共振波谱仪器来自布鲁克的EMXplus电子顺磁共振波谱仪。
