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[user interviews] EPR spectrometer as track "health killer" becomes a powerful tool for atmospheric pollution
takeaway
In order to further explore the dangers of air pollution on human health, identification and monitoring of atmospheric particulate matter in the oxidation of the generation of free radicals and to determine their performance is the focus of scientific research workers.Instrument information network has had an interview with professor Chen Qingcai shaanxi university of science and technology, ask him to introduce the forefront of these research results.
Professor Chen Qingcai
Long life free radicals: for a long time, persistence, are the important factors of health damage
Instrument information networkResearch focus: please brief us on the current atmospheric pollution, as well as the main research direction you now?
Chen Qingcai: air pollution is one of the most complex environmental problems in China, the related research is very hot, in the past few years has made significant governance on the governance of fine particulate matter, the next few years national strategy will focus on the collaborative management of fine particulate matter and ozone.
Control air pollution, however, is not our ultimate goal, but the realization of human healthy living environment and process.Therefore, the health effects of air pollution is the hot spot of research in this field, my main point of interest is also in this research direction.We are committed to explore human health damage caused by the specific material of atmospheric particulates, and the causes of the impact human health, which is based on for your own contributions to our country people's physical health science and technology strength of this belief.The current study found that produce reactive oxygen free radicals of atmospheric particulates is the important way to endanger human body health, recent studies we pay special attention to long life free radicals (EPFRs), because it can bring a long time, persistence, damage the health of mankind a great "health killer".
Instrument information network: please briefly introduce active oxygen free radicals and its health effects of atmospheric particulate matter?Your team specific what research?
Chen Qingcai: there are many kinds of active oxygen free radicals, hydroxyl radicals are so common, super oxygen free radical, etc.Due to the lack of electronic material is a kind of free radicals in the body after may take cellular protein molecular electronics, make protein in branched chain alkylation, distortion and of cancer.
This group is committed to focus on long life free radicals (EPFRs) in recent years, it is different from traditional life there are only a few milliseconds of free radicals, its life for months or even years, can continue to cause harm to human body health.Our study found that much of its exists in atmospheric particulate matter and significant health risks, such as severe haze period of xi 'an, 2017 EPFRs contents of PM2.5, equivalent to about 23 cigarettes per day to inhale the health hazards to be reckoned with.
EPR: "the only popular equipment direct analysis of free radicals,"
At present, the air pollution research mainly used what instrument approach?Electron paramagnetic resonance spectrometer (EPR) in the study of air pollution is mainly used to solve the problem of what?Compared to other analytical instruments have irreplaceable advantage?
For atmospheric pollution research instruments very much, have online, offline, phyletic and various, chromatography online instruments such as aerosols, organic carbon/carbon element analyzer, etc, offline instruments such as gas chromatography, Fourier infrared spectrometer are common atmospheric particulate matter such as analytical instruments.
And electron paramagnetic resonance (EPR) spectrometer is able to directly analyze the only popular equipment, free radicals are important device used in my research.Currently our team use the EPR is MS5000 (brooke ESR5000), mainly used for the analysis of the types and content of free radicals.Its principle is simply material containing unpaired electrons under external magnetic field effect, the energy level splitting, will happen at this time in perpendicular to the direction of the magnetic field exerts a certain frequency electromagnetic wave, and constantly changing magnetic field intensity, when the magnetic field strength just meet the conditions, the unpaired electrons can produce transition, electron transition of absorption signal would be handled by the electronics system available EPR absorption lines, different kinds of corresponding parameters and produce free radicals of spectral line is different.
Other free radicals detection methods, such as spectrophotometry, fluorescence probe method can deal with more complex samples and its more for indirect testing, qualitative quantitative free radical effect is not ideal.EPR can not only directly determine the content of free radicals and types, and in the process of atmospheric samples tested tend not to damage the original sample, so that more conducive to subsequent other detection of the sample.In addition, the EPR also can online detection of free radicals, to explore the time curve, etc., the production of free radicals are important advantages of EPR.
It is understood that your group is the domestic earlier MS5000 was applied to atmospheric pollution research team, would you please tell me why then would choose MS5000 this instrument?
At home and abroad to MS5000 (brooke ESR5000) use is in the field of materials and biological, more research in the field of atmospheric relatively less also.Select MS5000 (brooke ESR5000), although there have been related literature support, but we still through the careful research and consideration.We choose the instrument main consideration equipment quality and enterprise service two factors.At that time, on the basis of the project put forward the demand for equipment specifications and requirements, and prototype verified the performance on the spot.In fact, in the process of buying also compared the other related EPR equipment of the company.Finally under the condition of meet technical requirements of subject, and considering the price, service, etc, choose the MS5000 comparison can meet the demand of our team.
We have learned, in October 2019, brooke acquired Magnettech EPR business, the business change after-sale, and other services to users are affected?
Almost no effect, the original instrument daily maintenance, software updates, consumables and replacement, product technical support to continue, basic technical issues arising in the process of instrument use will get the other engineers and technical personnel and abroad solution is given.Brooke's very famous at the level of technology and business, we hope in the future to the next level, strengthening the frontier technology and application of exchanges and promote cooperation.
Cutting-edge research results: EPFRs composition and source of parsing
Instrument information network: MS5000, based on your research work which representative research results achieved?Which solves the key problem?
Chen Qingcai: based on MS5000 (brooke ESR5000), we in the atmospheric particles new health risks - long life has made a series of free radicals (EPFRs) research results, in ES&T, ACP, EP, AE in areas such as TOP journals published more than 10 academic papers.MS5000 help me solve the problem of the EPFRs analysis, we have our own independent property rights for EPFRs detection method of atmospheric particulates and data processing soft opened up the research direction of bottleneck.
In EPFRs research, our team for the first time by organic matter in atmospheric particulates are put forward in the high temperature effect the production of graphene oxide class material is a key source of generating mechanism and EPFRs, and the mechanism is verified by a series of experiments, this different from the traditional metal oxides leading EPFRs generated view;Another major research is the main source of EPFRs research, based on the research of xi "an annual sample, we found that the source of combustion and atmospheric dust is the main source of xi" an atmospheric EPFRs.
Instrument information network: the future, based on epr spectrometer, your team will also conduct research work?
Chen Qingcai: our team will continue to use the EPR study of atmospheric particulate matter produce reactive oxygen free radicals, further clarify the mechanism of health risks to atmospheric particulate matter, for our country the improvement of people's health to provide scientific advice and guidance.Based on the existing research results, we need to explore the specific mechanism of EPFRs harm human health, such as its is how to generate reactive oxygen species and function of human body cell, and the generation of reactive oxygen species and ability, the research to explore the health risks of atmospheric particulate matter has very important value.
Instrument information network: based on the requirements of scientific research and using experience, what are you think now electron paramagnetic resonance spectroscopy technique need to enhance or improve?What are you looking forward to more with new technology
Chen Qingcai: currently in the process of instrumentation, the main problems is the stability of instruments, such as the study of atmospheric samples often require months of continuous testing, and will appear in the process of EPR continuous boot baseline offset problem, hope that manufacturers can in the later for instrument stability accordingly in the technical upgrade of optimization.
In the future, I think we should strengthen the research and development of special applications, such as atmospheric particulate matter analysis in our study did not specifically targeted before accessories or method.In addition, it is recommended that the development of online analysis components and technology, strengthen the data processing software of automatic parsing function, etc.
