Intellectual property rights
Why do you want to pay attention to intellectual property?
Patent is the inherent risk industry, also provide the opportunities for generics firms.On average, the drugs within 3 years after the patent expires the profits will be reduced by 90%.Method has several patents for longer periods, such as drug combination, a new application, dosage, new isomer and solid form or formula and so on.
In the form of patent drug ingredients provide strong protection of intellectual property rights, encourage drug companies to invest long-term, expensive, ultimately promote the medical progress, and provide funds for future research.
By the method of using solid form patent may add the ingredients for the drug patent protection.Either increase additional claims related to the solid form, either for additional solid form related to the composition of the initial drug patent patent.Solid form here refers to the crystal (polycrystal, hydrate, dissolved, salt, eutectic) and amorphous materials (amorphous material, amorphous solid dispersions and eutectic).Due to solid form are usually in the first ingredient after the patent application, therefore, their patent validity may be longer.
This strategy is likely to be successful, is based on a novel and non-obvious.For any compounds, we can't predict how many different solid form or their features, these are not obvious.In addition, by definition, every kind of new solid form is almost new.As a result, almost every kind of new solid form are likely to be the subject of patent.
Brooke provides a series of comprehensive analysis system, used for characterization of solid form, thus power strong patent application and the subsequent patent protection.X-ray diffraction (XRD) data is usually considered a representation form required by the necessary condition, usually with complementary infrared (IR), Raman and/or solid nuclear magnetic resonance (ssNMR) data for further characterization.
Brooke solution about patent protection
Unique is that the XRD can directly detect molecules are arranged in the form of solid.Therefore, XRD is possible any form of crystal structure analysis and relevant properties characterization of the tool of choice.XRD pattern and derivative peak list powder is a kind of fingerprint, both as a single phase and in other mixture of solid materials, can verify the polymorphism of a given crystal form, and to quantify the abundance in the mixture.XRD fingerprint can also determine the polycrystal purity of a given sample, and the different to quantify the abundance of polycrystal.Therefore, XRD fingerprint is usually considered a gold standard characterization of solid materials, and often used to define the patent and patent protection.
Solid state nuclear magnetic resonance (ssNMR) is a kind of complementary technology, can be used to solve any potential questions the morphological characteristics of the solid.SsNMR can measure the relaxation time, solid form in a particular area.When you need a higher resolution or analysis and quantification of amorphous form, ssNMR is particularly important.As a powerful and rich in information technology, the structure of ssNMR provided valuable information, in order to enhance your solid form representation of drugs and drug products.
Brooke's high-end instrument to study fully solid form, using a variety of technology, provides the results of the analysis from multiple angles.Characterization of full and accurate quantitative to ensure the quality, at the same time protect the right to your market.Original and generic drug companies to deal with the solid form of intellectual property litigation costs can be as high as millions of dollars, and when that happens, the original natural hope to master the best data.
LabScape
Brooke BioSpin nuclear magnetic resonance (NMR) and preclinical imaging products, services and lifecycle support
Brooke promises to provide clients with unparalleled throughout the buying cycle, from the initial consultation to the evaluation, installation, and service life of the instrument, it is LabScape always adhere to the service concept.
LabScape Maintenance agreement (Maintenance Agreements), the optional services (On - site On - Demand) and laboratory improvement plan (Enhance Your Lab) modern Lab is dedicated to provide you with a new method of Maintenance and service.