The resolution to the next level: addressing the challenges facing society
Gottingen in Germany's Max Planck institute of institute of biophysics, 1.2 GHz of nuclear magnetic resonance spectrometer
Solid phase and liquid phase using nuclear magnetic resonance (NMR) analysis of biological molecules
Their research including important globular proteins, the structure of membrane protein and protein complexes, dynamics and function.
Ultra-high field nuclear magnetic resonance (NMR) is unique, it can study the inner disorderly proteins (IDPs) properties and interactions, and these proteins account for 30-50% of the human proteome.Displaced in the basic rules of play a key function in the cell biology, disease biology they are in many cases.
1.2 GHz at the ETH Zurich
1.2 GHz at the ETH Zurich
The Bio - NMR group, headed by Roland Riek, is part of The Laboratory of Physical Chemistry at The Department of Chemistry and Applied Biosciences of The Swiss Federal Institute of Technology (ETH) in Zurich.
Nuclear Magnetic Resonance Spectroscopy (NMR) is one of the principal experimental techniques in structural biology to determine atomic resolution structures and to investigate the dynamic features and i雷竞技怎么下载ntermolecular interactions of in macromolecules. Using NMR as a major tool, the objective of the research in our group is to understand the conformational switches of proteins associated with amyloid diseases and trans - be signaling.
1.2 GHz at the University of Dusseldorf/Forschungszentrum Juhlich
1.2 GHz at the University of Dusseldorf/Forschungszentrum Juhlich
The function of each cell and each organism decisively depends on The dynamic interactions between in macromolecules and on their correct three - dimensional structure. The Faulty interaction and incorrectly folded structures eventually lead to diseases and ageing.
The aim of The Institute for Physical Biology at The Heinrich Heine University of Dusseldorf is to understand these interactions and to determine The three - dimensional structure of The protein complexes involved in decisive cellular The processes - if possible, in atomic resolution.
They are interested in understanding the structural features of life 's key players and use their insights to identify new therapeutic opportunities to interfere with diseases - related to the processes.
In this new one the Etzkorn Group at the Institute for Physical Biology of the Heinrich Heine University In Dusseldorf focuses on the following switchable viewer:
Be systems in neuronal signalling, NMR method development, Biocatalysis.
1.2 GHZ at Utrecht in the ultra - high field facility of the Netherlands
The ultra - high field NMR of The Netherlands
The uNMR - NL facility enables non - invasive characterization雷竞技怎么下载 of molecular systems, from The atomic to micrometer range by ultra - high field NMR. The current uNMR NL - high - end 1.2 GHz spectrometer is equipped with The state - of - The - art instrumentation for all three fields of research, providing The highest sensitivity and resolution in The Netherlands. Moreover, dedicated NMR instrumentation and expertise is available at four uNMR - NL sites.
The uNMR - NL facility offers expertise and access to The state - of - The - art magnetic resonance equipment for applications across indicates The Netherlands.