Brooke and ANPC cooperation to cope with the challenge of the new champions league pneumonia

By world famous phenotypic omics pioneer and scholars led by professor Jeremy Nicholson ANPC research team, working with SMW health new crown pneumonia response teams, and a wider range of western Australia (WA) health care community cooperation, and has set up a major project research and diagnosis, in order to better understand and predict the evolution of the new champions league pneumonia severity, complex genetic influence and determine its pathogenicity, and the interaction between environment and way of life.Then they will be involved in clinical trials of new antiviral drugs, and to predict population after the vaccine available to vaccine response results.

Accelerate the diagnosis time

Our goal is to accelerate the time to provide solutions for diagnosis and prognosis.And most important, risk of infection in patients with severe need quick assessment, thus helping to guide and optimize the path to clinical treatment.ANPC researchers will use the most advanced range of brooke instruments, including Avance IVDr nuclear magnetic resonance (NMR) and timsTOF Pro ion mobility spectrum, the impact II QTOF mass spectrometry and solariX MRMS mass spectrometry, combined with the data modeling method, the plasma and urine sample molecules, physical and biochemical characteristics of metabolism of extensive and in-depth analysis, so as to establish informatization transformation model.The change of these models to predict the severity of disease, and help to understand the different reaction of therapeutic intervention.

Prof Nicholson said: "in ANPC, we will at least one year will be 100% of all resources into new champions of the fight against pneumonia.This is the planet's largest emergency medical challenges, and we are in Australia and even worldwide are equipped with the most perfect metabolism laboratory, at the same time we also have the superior clinical and hospital architecture, and we have a responsibility to bear such research work.""We are united by Simon Mallal professor and Mark Watson team, led by associate professor genomics is to determine the disease specific biomarkers, and thus find out the infection patients, by severity of risk stratification of patients and evaluation for the treatment of patients with real-time response."

Promote clinical research of scientific cooperation relationship

Brooke group President and CEO, Frank h. Dr Laukien commented: "we are firmly committed to the scientific and technical support for professor Nicholson's team.Murdoch university about the new crown pneumonia clinical research plan is very good, for the disease, prognosis and treatment of metabolic biomarkers feedback model for comprehensive research."

"I particularly hope the team can find as soon as possible to prove the clinical scheme, in order to reduce the new champions league second stage life-threatening pneumonia mortality in lower respiratory tract infections.Medical community urgently need to determine whether the broad-spectrum antibiotics and (or) immune inhibitors can improve the survival rate of the second stage, the viral pneumonia, potential bacterial pneumonia or entilator-associated pneumonia (VAP) and by our own immune system of cytokine storm cause lung inflammation, seems to be caused by a series of very dangerous complications."

Unique biological specimen collection ability

ANPC will to cooperate with a number of scholars in this project, including those from murdoch university and the university of Notre Dame Merrilee Needham professor and professor Toby Richards from the university of western Australia.They will be sent to you by the west Australian health led by Gary Geelhood transmission network (WAHTN), for the new crown pneumonia response teams together WA's top doctors and researchers.We expect that all new crown pneumonia patients in hospital and then to accept clinical trials will be ask permission, ANPC will study from experiment and testing of samples, including longitudinal urine and plasma metabolic monitoring, etc.

Richards, professor in the comments WA unique status in the team, said: "we are in the second wave in the spread of the new champions league pneumonia, so we have the opportunity to prepare for dealing with it.We have established a unique platform in WA, used to collect data and biological samples patients, so as to fully understand the disease and patient response to therapy."

To reduce the current and future threats

To understand the infection and biological consequences will contribute to the development of effective treatments and vaccines, thus alleviate the current threat to tens of thousands of people around the world.This groundbreaking work will also enable us to cope with the viral pandemic ready in the future.Avance IVDr nuclear magnetic resonance (NMR), timsTOF Pro ion mobility spectrum, the impact II QTOF mass spectrometry and solariX MRMS mass spectrometry analysis tools for research use only.

The Australian national phenotypic group led by murdoch university learning center (ANPC) will not only in Australia, and in the global change people's life and the quality of life.ANPC work support almost all of the biological sciences.It crossed the traditional field of research and develop a new, more collaborative scientific research method.In the long run, ANPC hope to build "world atlas" of human disease research, thus insight will benefit each and every one of the world's future health risks.As the only such research in the southern hemisphere, ANPC collected 5 colleges and universities in western Australia and frontier health and medical research institutions.It is also connected with international phenotypic omics center network, also has been widely used in agriculture and environmental science.ANPC Perth and western Australia may be defined as precision international leader in the field of medicine, and in prediction, diagnosis and treatment of diseases of major leap.It is a part of murdoch university institute of health in the future.

Science and technology and the partner

ANPC equipped with a variety of the most advanced nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) instrument, all from ANPC strategic partner brooke byatt's and brooke Dalton.Brooke is a production of molecules and materials research and analysis of scientific instruments and industrial application of manufacturers.

Phenotypic omics

The phenotypic group is a dynamic fingerprint of unique biological characteristics, is by the environmental and genetic factors between the result of a complex interaction.Phenotypic group study environment and people's way of life how to interact with their genes, which affects their health and disease risk.Metabolic phenotype analysis is at the molecular level of biological tissues and fluids is analyzed, in order to reveal the genetic, environmental and lifestyle factors such as the specific interaction between.

Professor Jeremy Nicholson

Leading Australian national center (ANPC) phenotype omics prof Nicholson is metabolic phenotype omics and system medicine as the pioneer of international reputation.He served as vice President of the institute of health in the future, murdoch university at present.Prof Nicholson has published more than 800 by the peer evaluation in terms of molecular mechanism of human body system of medical papers.As a member of the British medical academy of sciences, professor Nicholson came to WA served as MRC - NIHR before founding director at the national center for phenotypic omics.In addition, he also served as head of the center of surgery and cancer research.Nicholson is currently a professor at imperial college London, emeritus professor of biological chemistry.

Professor Elaine Holmes

A pioneer another system of medicine, professor Holmes is the British academy of medical sciences of highly cited scholars and researchers.Professor Holmes arrived from imperial college London before WA, a former head of the computing and system.Murdoch university in Australia, national center for phenotypic omics Holmes researcher professor calculation, a professor of medicine and the prime minister's chair award.She has also served as professor at imperial college London chemical biology.

Dr Ruey - Leng Loo

Murdoch university ANPC senior lecturer, the prime minister for intermediate researcher

Professor Toby Richards

University of western Australia, Michael Lawrence Brown surgical chairman, professor emeritus at university college London, clinical test methodology, research response, director of the new champions league pneumonia

Professor Merrilee Needham

Murdoch university, the university of Notre Dame and Fiona Stanley hospital, senior consultant, the study director

Brooke is committed to supporting scientists acquire the groundbreaking scientific discoveries and new applications are developed to improve the quality of life of human beings.Brooke's science and technology of high performance instruments and high value analysis and diagnosis of solution, allow scientists to the molecules, cells and micro level to explore the mysteries of life and material.In close cooperation and user, brooke devotes to the scientific and technological innovation, improve productivity and achieve the success of the user.Our business areas include molecular life science research, and drug application, microscope and nanometer analysis, industrial application, cell biology, preclinical imaging, clinical phenotype omics, proteomics research and clinical microbiology and so on.