Cancer metabolomics research based on nuclear magnetic resonance (NMR)

Although in the early detection and treatment strategies made progress, but the cancer is still the leading cause of death in the world.Because of the complexity and heterogeneity of tumor biology may have different outcomes for patients with similar cancer diagnosis and response to treatment.Metabolomics is a branch of omics technology, involving metabolic group of small molecule metabolites of high flux identification and quantification.

Cancer cells must be able to turn nutrients for a living material, maintain energy generated at the same time, the need for reprogramming center metabolic process.This phenomenon is more and more is considered to be a potential target for treatment, also can be used for prognosis and risk stratification and treatment monitoring of the source of biomarkers.

Based on nuclear magnetic resonance (NMR) * cancer metabolomics research can cover all aspects of the analysis of pipeline, so that through the following ways to determine the prognostic and predictive biomarkers.

• Confirm with specific metabolic characteristics related to different types of cancer
• At all stages of cancer development to provide important information
• Through the work process standardization, data validation process, multicenter study strengthen clinical transformation and data sharing

The Norwegian university using nuclear magnetic resonance (NMR) for breast cancer research

Tone Frost Bathen
The Norwegian university of breast cancer research
Norway NTNU nuclear magnetic resonance (NMR) technology, a professor of nuclear magnetic resonance (NMR), head of the cancer study group

At the university of tubingen in using nuclear magnetic resonance (NMR) to cancer research

Christoph Trautwein
Metabonomics and the system of medical team leader
Hospital of the university of tubingen in Germany

* brooke's nuclear magnetic resonance (NMR) product is for research use only, not for any clinical diagnostic procedures