TCI trace low temperature probe
Brooke Biospin 1.7 mm TCI MicroCryoProbe ™ is a commercial ultimate tool can provide unparalleled quality sensitivity.It can achieve the highest sensitivity of 1 h, and enhance the performance of the carbon channel.
This kind of extremely high sensitivity jumped to 1.7 mm MicroCryoProbe become ideal sample size limited NMR analysis tools, such as natural products, separation of low abundance proteins, peptides, or small molecules, it is difficult to express proteins, etc.
For many samples of "real life", the use of the probe is the only way to solve the collection difficult spectra.Natural products are usually only micrograms, or biological samples because of its expression quantity is not big, or screen thousands of compound screening benefit from the reduction in the number of goals for all of these applications are using the 1.7 mm in TCI MicroCryoProbe after have been significantly increased.
application
TCI MicroCryoProbe sample application has the following:
protein
U - 13 c / 15 n white element - 1 b from 1 ml QIAGEN EasyXpress cell free kit expression
15 n/U - 5% - 13 c marker protein by Guy Montelione NESG provided.
Small molecules
Retrorsine samples provided by the first spirit plog research institute Gary Dr. Martin.
The technical details
- Proton optimization three resonance NMR probe
- The sensitivity of 1 h compared with traditional 1.7 mm probe increased 6 times
- Four independent channels (and lock channel)
- In more than X nuclear (e.g., 13 c and 15 n) on decoupling at the same time
- 2 h of cooling preamplifier, the stability of excellence
- ATM (automatic tuning and matching) compatible
- 30 mu L total sample volume (the elution volume of volume and HPLC - SPE exactly match, very suitable for automation)
Sensitivity to improve
For a given amount of material, compared with the conventional 5 mm probe, gain for 14 times, 6 times on conventional 1.7 mm probe to realize gain.In some cases, this may result in the experiment time reduced by more than 200 times.
2008 R&D 100 prize awarded brooke BioSpin, the 1.7 mm triply resonance NMRI MicroCryoProbe ™ the sample volume is only 30 mu L the breakthrough of sensitivity.
LabScape
Brooke BioSpin nuclear magnetic resonance (NMR) and preclinical imaging products, services and lifecycle support
Brooke promises to provide clients with unparalleled throughout the buying cycle, from the initial consultation to the evaluation, installation, and service life of the instrument, it is LabScape always adhere to the service concept.
LabScape Maintenance agreement (Maintenance Agreements), the optional services (On - site On - Demand) and laboratory improvement plan (Enhance Your Lab) modern Lab is dedicated to provide you with a new method of Maintenance and service.