Life science and micro - CT

SkyScan 2214

Nanoscale three-dimensional X-ray microscope

A perfect performance

You control

Bright spot

Bright spot

300 x 400 mm
Can accommodate the largest sample size
Whether the sample is big or small, SKYSCAN 2214 can flexibly imaging to them
160 keV
penetration
Quickly switch the filament, the realization of the highest penetration of tungsten filament and can achieve the highest resolution six boride lanthanum filament switching
< 500 nm
The real 3 d spatial resolution
Define the resolution method are many, but the most important thing is to generate the 3 d model of parsing out the two characteristics

SKYSCAN 2214 - nm X-ray microscope

New multiscale SKYSCAN 2214 X-ray nanoscale tomography system, can use one instrument to cover the broadest object size and spatial resolution.It for three-dimensional imaging of geological materials and created a unique, accurate modeling is suitable for oil and gas exploration, composite materials, lithium battery, fuel cell, electronic components, and lung or tumor vascularization in vitro before clinical application.

To reach more than 300 mm diameter large objects, the instrument of their internal microstructure scanning and three-dimensional reconstruction;For small size of the sample, the instrument can achieve sub-micron resolution.

The system has an "open" transmission type X light source, the spot size is less than 0.5 microns, and own diamond window.It can be equipped with up to four X-ray detector for maximum flexibility, suitable for large flat panel detector of the object, wide field 11 mp cooled CCD detector, the medium view 11 mp cooled CCD detector, achieve the highest spatial resolution 8 mp cooled CCD detector.Automatic variable acquisition method and phase contrast enhancement, makes in a relatively short scanning time to achieve the best possible quality.

SKYSCAN 2214 with 3 d software SUITE.This comprehensive package covers the GPU accelerated reconstruction, 2 d / 3 d shape analysis, as well as surface and volume rendering visualization.

SKYSCAN 2214 walk - up video

What is XRM?video

The characteristics of

The main features

SKYSCAN 2214 characteristics

The light source

SKYSCAN 2214 using the latest generation of open X light source.The light source can be achieved is better than the actual spatial resolution of 500 nm, 160 keV X-ray energy, and power of up to 16 W.Because have very simple registration in advance of the filament replacement program, the light source is hardly needs to be maintained.

SKYSCAN 2214 with diamond Windows open (pump) nano focus X-ray sources.It can produce peak energy range from 20 kV to 160 keV X beam, and there are two types of the cathode.Tungsten (W) cathode applies to a maximum of 160 kV complete acceleration voltage range, minimum spot diameter of 800 nm.Six boride lanthanum (LaB6) cathode applies from the acceleration of 20 kV to 100 kV voltage of X-ray beam spot size can be smaller than 500 nm, to ensure the highest resolution in imaging and 3 d reconstruction.JIMA resolution test card shows that it can easily parse out the structure of 500 nm.In order to ensure that the position of the focal spot size and source can remain stable for a long time, X light also can equipped with water cooling system, the system contains a loop device, can accurately control the temperature of the cooling liquid in order to maintain the stability of the temperature.

SKYSCAN 2214 characteristics

The detector

In order to achieve the maximum flexibility, SKYSCAN 2214 can be equipped with up to four X-ray bomb detectors: three with different resolution and field of CCD detector, and a large size of the flat panel detector.To select all detectors are available by clicking the mouse.Different CCD detector can be in any time within the system life cycle to be modified.

Three CCD detector can be at the center of the beam and two offset pictures, so as to make the double field range.By offset compensation and intensity difference correction, the two offset can be automatically mosaics of images taken together.

When using small pixels of a CCD detector, the large size of the object can also high resolution imaging and 3 d reconstruction.The flexibility of built-in detector can make it according to the object size and density adjustment field and spatial resolution.Local reconstruction through advanced large samples, it can with high resolution scanning a particular part of a larger object, and get the same high quality images.

In addition, by using the detector's offset and vertical movement of the object, but also expand the field of view from the horizontal and vertical direction.

SKYSCAN 2214 characteristics

In situ test rig

With highly accurate sample 2214 SKYSCAN, support up to 300 mm diameter and weight of up to 20 kg object.Air suspension rotation motor can precisely at very high accuracy rotating object position, integration of precision positioning platform can guarantee the sample completely aligned.

SKYSCAN 2214 has a very big sample room and easy to use, convenient scanning large objects and install an optional test rig.It has enough space to accommodate the peripheral equipment.

Brooke's material test bench can be maximum compression test of 4400 N and 440 N tensile test.All test bench can be contacted automatically by the system of the turntable, without any external cables.Through the use of software provided, can set the scheduled scan test.

Brooke's heating and cooling units can reach the highest + 80 DHS C or below the lowest environment temperature low temperature of 30 DHS C.And other test bench, heating and cooling units do not need any extra connection, the system can automatically identify the different test rig.Through the use of heating and cooling, the test samples under the condition of the environment, to assess the micro structure of the temperature of the sample.

SKYSCAN and DEBEN test-bed is fully compatible with 2214.With the aid of own adapter, DEBEN test-bed can easily be installed to the SKYSCAN 2214 rotary table.

The cooling stage
Material testing phase
Deben phase

application

The key application

Mineralized tissue

SKYSCAN 2214 nano CT imaging can provide real ultimate performance.Installed four camera: a big size 6 million pixels cMOS tablets, used for high voltage and large samples of skeletal or dental imaging, and three small size detector, for every conceivable bone scan sample to provide the best choice of the resolution and X-ray energy window.

Sub-micron voxel scanning can provide glittering and translucent get rid of mineralization of bone fracture and micro-scale structure, as well as nano-scale resolution support structure of biological materials.

Phase retrieval (Paganin) provides a new dimension to the analysis so far few studies of bone mineralization model.

Using sheep orthopaedic research, primates or similar model, can use 14 cm scan vision and 160 kv X-ray source.Through mechanical test and temperature control phase you and orthopaedic biomechanics research goal.

Shape measurement has the full 3 d and 2 d parameters of density measurement includes preclinical size within the scope of the BMD calibration reference.Advanced 3 d image analysis function including 3 d registration, adaptive threshold, euler connectivity, fractal, anisotropy and stereo, filtering, the Boolean logical operators and so on.

Soft tissue

Biological tissues in vitro nanometer CT scans, the pixel size of submicron, like histology or electron microscopy, but it's true, deep 3 d - this is a non-destructive method shows the internal structure of the wonderful.Contrast agent or chemical drying can be further enhanced or differentiate tissue density to improve image quality.SKYSCAN, 2214 in new imaging disciplines, micro CT histology and tissue morphometry, plays a leading role.

Unique versatility this system ensures that each sample can be to optimize the parameters, the best resolution and contrast scan.

Four camera: a 6 million pixels large flat-panel camera, imaging for high voltage and large tissue samples, and three small format cameras, for every conceivable sample scanning resolution and the best choice of the X-ray energy window.

Comprehensive ability of 3 d image analysis, including morphology and density measurement, 3 d registration, segmentation and advanced image processing methods.

Plants and animals

Micro - CT to the most remote part of the internal structure of biological visual effect is very good.This imaging method can create a nanoscale figure 3 d X-ray attenuation, and do not harm or damage scanning object.Almost all of the biological tissue can be visualized and analyzed, little or no special sample treatment.Sub-micron voxel resolution can be for small insects and plants or seeds structure imaging, has strong ability of amplification and rich in details.

The accuracy of the scanning room space and the turntable ensures that all types of samples can be scan, from small samples of zebrafish and save the zoology and botany to potted plants and rocks buried fossil.

Four cameras installed: a 6 million pixels large flat-panel camera, imaging for high voltage and large samples, there are three small format cameras, for every conceivable biological sample scans provide the best choice of the resolution and X-ray energy window.

Software suite can use the full 3 d and 2 d shape measurement parameters, advanced 3 d image analysis function including 3 d registration, adaptive threshold, euler connectivity, fractal, anisotropy and stereo, filtering, the Boolean logical operators and so on.

Technical parameters

SKYSCAN 2214 technical parameters

Characteristics of the

parameter

advantage

X-ray source

20-160 kilowatts

The biggest 16 W

The user can replace filament

Optimized can realize the maximum energy (W) or the highest resolution (LaB6)

Rotating diamond Windows can achieve the longest service life

X-ray detector

6 million pixels of flat-panel detectors

11 million large size cooling CCD camera

Size cooling CCD camera in 11 million

8 million high resolution cooling CCD camera

Different pixel size and the detector size, convenient in the detector resolution, balance between coverage and count statistics

Can provide 1, 2, 3, or 4 a detector

Allow the upgrade to increase the detector

Image format

A single scan up to 8000 x 8000 x 2300 pixels

By allowing the user to select the image size, make can balance data set size and resolution as needed.

Software to streamline the collected data

The spatial resolution

Minimum of 60 nm pixel size
< 500 nm low contrast resolution (MTF) 10%

Simple graphical control, can choose according to the detector, sample and the probe distance resolution optimization experiment.

Adjust the focal spot size of light source, in order to balance the power and resolution

Positioning accuracy

Rotation accuracy is better than 50 nm,
Equipped with pneumatic adjustment shockproof granite platform

Air suspension sample machine makes sample machine can rotate smoothly

Samples can be used in a simple chuck installations

Mechanical and electrical interface to make it can be used as advanced materials research platform

The largest object dimension

300 mm diameter (140 mm scanning size)

Length is 400 mm

Maximum weight 20 kg object

Have the energy and space scanning large size sample

Small sample can be precisely locate near the light source, in order to realize the maximum amplification

size 1800 mm x 950 mm x 1680 mm (deep x width x height)

Weight: 1500 kg

Efficient design can optimize the use of space

Large chain sliding door convenient maintenance

software

Location, scanning, reconstruction and analysis

XRM software

Brooke XRM solution includes all software needed to collect and analyze data.Intuitive graphical user interface, the user support expert and novice users boot parameters optimization.By using the latest GPU power algorithm, greatly shorten the reconstruction time.CTVOX、CTAN 和 CTVOL 组合成强大的软件套件,用于模型的定性和定量分析。

Measuring software:
SKYSCAN 2214, instrument control, measure planning and collection

Reconstruction of software:
NRECON - the 2 d projection image is converted into a 3 d volume

Analysis software:
DATAVIEWER= for 3 d volume and 2 d / 3 d image registration according to the examination
CTVOX- by volume rendering realistic visualization
CTAN= 2 d / 3 d image analysis and processing
CTVOL= to be exported for CAD or 3 d printing surface model visualization

News and events

support

SKYSCAN 2214 - service and support

Optional services include:

  • Experienced troubleshooting experts to provide you with help desk support, to isolate and solve the problem of hardware and software
  • Network-based remote instrument services, diagnostic and application support for service
  • With the Help from "combined the reality of the support services: virtual engineer on your side (video)
  • According to your request for planned maintenance
  • Customer on-site repair and maintenance services
  • Worldwide is usually the next day or several days can provide spare parts
  • Installation identification, appraisal/performance verification of compliance services
  • Site planning and relocation

Brooke support:

In the brookServices and support websiteYou can find the following resources:

Software updates

  • Registered users can manage system software update online

Supporting documents

  • Registered users can get product manuals and online installation guide

LabScape

Brooke BioSpin nuclear magnetic resonance (NMR) and preclinical imaging products, services and lifecycle support

Brooke promises to provide clients with unparalleled throughout the buying cycle, from the initial consultation to the evaluation, installation, and service life of the instrument, it is LabScape always adhere to the service concept.

LabScape Maintenance agreement (Maintenance Agreements), the optional services (On - site On - Demand) and laboratory improvement plan (Enhance Your Lab) modern Lab is dedicated to provide you with a new method of Maintenance and service.

LabScape - Remote Monitoring