MRI probe at low temperature

MRI low temperature probe used in mice

High sensitivity of MRI probe at low temperature

High sensitivity of MRI probe at low temperature

Compared with the standard room temperature radio frequency (rf) coils, brooke MRI CryoProbe raised living detection sensitivity by 2.5 to 5.3 times

Brooke provides suitable for BioSpec ® and PharmaScan ® line of MRI CryoProbe ™.It USES magnetic resonance imaging (MRI) at low temperature, cold head MRI refrigerant technology and processing method can maintain very low temperatures, and using rf coil and preamplifier, closed-loop circulating cooling in the applications of conventional MRI, compared to the standard of the product at room temperature radio frequency (rf) coils will live improves the sensitivity of 2.5 to 5.3 times.In addition, it in small animal MRI has set a new SNR.

The main features

  • Sensitivity increased by 2.5 to 5.3 times in the body
  • 更高的空间分辨率和更短的扫描时间
  • Design a flexible, easy to place
  • Through monitoring and insulation measures, avoid cold surface contact with animals
  • 在磁体外冷却
  • Meet all the requirements about the safety of users and animal

The technical details

MRI probe technology at low temperature

Brooke MRI probe system in low temperature radio frequency (rf) coils and preamplifier with closed cycle refrigeration system to cool down.Due to rf coils and related electronic components sample thermal noise and noise, thus greatly reduce the noise can significantly improve the MRI signal to noise ratio.Brooke BioSpin CryoProbe is used for high resolution NMR technology pioneer, in the past 14 years, customers around the world have installed more than 1300 sets of CryoProbe.

MRI冷冻器相比于标准的室温射频线圈提供了极大的信噪比提升:

  • Resolution is as high as 20 (including m in the body
  • The shorter measurement
  • 室温线圈不适用的新应用(高分辨率,fMRI…)
  • The shorter anesthesia
  • 由于测量时间更短,因此研究变得更加经济有效

Easy to use CryoProbe Settings

MRI冷冻器的动物处理和监护非常类似于标准的室温射频线圈.CryoProbe冷却可在磁体外部实现,确保扫描仪时间得到最佳使用。

MRI CryoProbe series: 4 species, covering all applications

1. The proton orthogonal transmit receive an MRI CryoProbe, gradient for 105 mm or larger gradient

Bruker in BioSpec ®, PharmaScan ® and ClinScan ® product line provides the MRI in the CryoProbe ™.In conventional MRI in application, the product compared to the standard of room temperature radio frequency coil sensitivity could be improved by more than 2.5 times.Available from 3 T to 15.2 T magnetic field intensity proton orthogonal transmit receive CryoProbe.

2. Used in 6 cm gradient orthogonal transmit receive one proton magnetic resonance imaging (MRI) of CryoProbe

The MRI CryoProbe specifically targeting has 6 cm gradient coil brooke mice scanner development, can also be used for BioSpec system equipped with 6 cm gradient coils.To BGA6S gradient of the proton orthogonal transmit receive an MRI CryoProbe is 7 T to 15.2 T standard products.

3. Used for 12 cm gradient and bigger gradient of proton four-channel control of phase array

Because of its enormous signal gain and therefore able to keep the resolution at the same time greatly shorten the scan time.Compared with room temperature 4 channel phase array coil, generally 2.6 times the SNR gain can be obtained.At present, the CryoProbes in 7 T and 9.4 T system provided as standard product.Other field is in development.

4. The combination of protons at room temperature radio frequency (rf) coils of nuclear magnetic resonance imaging (MRI) X CryoProbe

The letter gain benefit from the low signal-to-noise ratio of nuclear magnetic resonance frequency: nuclear resonance frequency is lower, the higher the SNR gain.Therefore, in the 13 c measurement can realize five times the signal-to-noise gain.Can provide other X according to the nuclear CryoProbe.

LabScape

Brooke BioSpin nuclear magnetic resonance (NMR) and preclinical imaging products, services and lifecycle support

Brooke promises to provide clients with unparalleled throughout the buying cycle, from the initial consultation to the evaluation, installation, and service life of the instrument, it is LabScape always adhere to the service concept.

LabScape Maintenance agreement (Maintenance Agreements), the optional services (On - site On - Demand) and laboratory improvement plan (Enhance Your Lab) modern Lab is dedicated to provide you with a new method of Maintenance and service.

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